方嘉佑 / Jia-You Fang
职称： 特聘教授
现职： 中醫學系天然药物硕士班 / Full-time Distinguished Professor
电话： 03-2118800 分機5521
学歷： 高雄医学大学药学所博士
专长领域： 药剂学、药物标靶与传输、化妆品学、奈米医学、天然物药理活性探究
个人网页：
研究室资料
研究室：藥劑學研究室/Pharmaceutics Laboratory研究室介绍连结
研究室成员：
博士班研究生1人、硕士班研究生8人、专任研究助理7人、博士后研究员1人
研究主题
药剂学研究在日本是属於医疗药学领域，在欧美国家则属药厂研发实务，其精神在於以既定药物赋予全新设计的处方、添加物或材料，以使药物本身之药理活性最大化或使其毒性及副作用最小化，或是延长药物於体内的留存时间。其意义在於使临床上的用药更加安全及有效，进而改善病患之依顺性。药剂学在药学研究领域内被视為较下游之药物研发过程，為一门应用科学，本研究室的主要工作便是為药物设计新的处方内容并探究其改善传统剂型缺点之程度与能力。
最近之研究计画:
- 多功能药物奈米载体经由 retinol-binding protein 4 (RBP4) 传输至肾臟以治疗抗药性菌血症诱发之肾损伤
- 多效能之蓝莓活性成分 pterostilbene 可塑性奈米微脂体：用以促进瓦解 P. acnes 生物膜结构与抗局部感染活性
- 接合 NIMP-R14 抗体的脂质奈米载体主动标靶至嗜中性白血球以改善 PDE4 抑制剂之抗乾癣活性
- 兼具被动与主动标靶能力之奈米载体传输 ciprofloxacin 以治疗感染性肺炎：以 IsaB DNA 為配体之非离子微胞
- 设计合成含有角鯊烯之前驱药及其奈米载体开发：以毛囊為标靶位置
- 厚朴有效成分之抗发炎及经皮吸收之研究
- 牛樟芝萃取物治疗异位性皮肤炎之研究：牛樟芝单苯环类化合物在角质细胞中的抗发炎机制
- 一系列合成异黄酮类化合物之经皮吸收参数建立与其乾癣治疗之活性探究
- 中草药多酚成分之最适分离技术开发
最近之产学合作计画:
- 中部科学园区管理局: 新剂型、新给药方式之痤疮 (Acne vulgaris) 用药-美诺四环 (Minocycline)-505(b)2新药开发
- 台塑生医: 保养品暨美容仪器经皮吸收及功效性研究
- 肌活丽学创研所: 乳铁蛋白抗白髮胜肽经皮吸收
- 大江生医: LipoMask 之经皮吸收能力评估
- 生达化学製药: VD-T03 处方优化与物理化学性质评估
- 信东製药: 硬镜去蛋白试验
- 元太科技: 新型药物贴片平台经皮肤传导能力可行性
- 药华医药: KX-01牛皮癣软膏之药物穿透研究
- 恩扬生物科技: 牛樟芝萃取物应用於治疗乾癣及异位性皮肤炎之抗发炎
论文着作
The selected publications from total 339 articles
*, corresponding author
- Tsai, M.J., Lin, C.Y., Trousil, J., Sung, C.T., Lee, M.H., Fang, J.Y.*, Yang, S.C. (2023) Proteinase K/retinoic acid-loaded cationic liposomes as multifunctional anti-acne therapy to disorganize biofilm and regulate keratinocyte proliferation. Int. J. Nanomed., 18, 3879?3896.
- Yang, S.C., Lin, C.F., Alshetaili, A., Aljuffalin, I.A., Chien, M.Y., Fang, J.Y.* (2023) Dual antibacterial and regenerative activities of platelet-rich plasma combined with β-lactam antibiotics are effective to treat MRSA-infected skin wound: the cell- and animal-based studies. Biomed. Pharmacother., 165, 115017.
- Huang, T.H., Chen, C.J., Lin, H.C.A., Chen, C.H., Fang, J.Y.* (2023) Self-nanoemulsifying drug delivery system-containing the poorly absorbed drug?valsartan in post-bariatric surgery. Int. J. Nanomed., 18, 2647?2658.
- Lin, C.Y., Yu, H.P., Chang, Y.T., Lin, Z.C., Alalaiwe, A., Hwang, T.L., Fang, J.Y.* (2023) Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via Ly6 antigen for psoriasiform dermatitis alleviation. Biomater. Sci., 11, 873–893.
- Nirmal, G.R., Lin, Z.C., Lin, C.H., Sung, C.T., Liao, C.C., Fang, J.Y.* (2022) Polydopamine/IR820 nanoparticles as topical phototheranostics for inhibiting psoriasiform lesions through dual photothermal and photodynamic treatments. Biomater. Sci., 10, 6172–6189.
- Lee, W.R., Chou, W.L., Lin, Z.C., Sung, C.T., Lin, C.Y., Fang, J.Y.* (2022) Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis. J. Control. Release, 347, 590–606.
- Tseng, C.H., Lin, C.F., Aljuffali, I.A., Huang, J.R., Yang, S.H., Fang, J.Y.* (2022) The effectiveness of synthetic methoxylated isoflavones in delivering to the skin and alleviating psoriasiform lesions via topical absorption. Int. J. Pharm., 617, 121629.
- Lee, W.R., Hsiao, C.Y., Chang, Z.Y., Wang, P.W., Aljuffali, I.A., Lin, J.Y., Fang, J.Y.* (2022) Cutaneous delivery of cosmeceutical peptides enhanced by picosecond- and nanosecond-domain Nd:YAG lasers with quick recovery of the skin barrier function: comparison with microsecond-domain ablative lasers. Pharmaceutics, 14, 450.
- Fang, J.Y., Huang, T.H., Chen, W.J., Aljuffali, I.A., Hsu, C.Y. (2022) Rhubarb hydroxyanthraquinones act as antiobesity agents to inhibit adipogenesis and enhance lipolysis. Biomed. Pharmacother., 146, 112497.
- Fang, J.Y., Chou, W.L., Lin, C.F., Sung, C.T., Alalaiwe, A., Yang, S.C. (2021) Facile biofilm penetration of cationic liposomes loaded with DNase I/proteinase K to eradicate Cutibacterium acnes biofilm for treating cutaneous and catheter infections. Int. J. Nanomed., 16, 8121–8138.
- Chuang, S.Y., Chen, C.Y., Yang, S.C., Alalaiwe, A., Lin, C.H., Fang, J.Y.* (2021) 2,4-Dimethoxy-6-methylbenzene-1,3-diol, a benzenoid from Antrodia cinnamomea, mitigates psoriasiform inflammation by suppressing MAPK/NF-κB phosphorylation and GDAP1L1/Drp1 translocation. Front. Immunol., 12, 664425.
- Nirmal, G.R., Lin, Z.C., Tsai, M.J., Yang, S.C., Alalaiwe, A., Fang, J.Y.* (2021) Photothermal treatment by PLGA-gold nanorod-isatin nanocomplexes under near-infrared irradiation for alleviating psoriasiform hyperproliferation. J. Control. Release, 333, 487–499.
- Lin, Z.C., Hwang, T.L., Huang, T.H., Tahara, K., Trousil, J., Fang, J.Y.* (2021) Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation. Theranostics, 11, 4567–4584.
- Liao, C.C., Yu, H.P., Yang, S.C., Alalaiwe, A., Dai, Y.S., Liu, F.C., Fang, J.Y.* (2021) Multifunctional lipid-based nanocarriers with antibacterial and anti-inflammatory activities for treating MRSA bacteremia in mice. J. Nanobiotechnol., 19, 48.
- Elzoghby, A.O., Abdelmoneem, M.A., Hassanin, I.A., Abd Elwakil, M.M., Elnaggar, M.A., Mokhtar, S., Fang, J.Y., Elkhodairy, K.A. (2020) Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier and targeting ligand. Biomaterials, 263, 120355.
- Tang, K.W., Lin, Z.C., Wang, P.W., Alalaiwe, A., Tseng, C.H., Fang, J.Y.* (2020) Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes. J. Dermatol. Sci., 99, 90–99.
- Alalaiwe, A., Lin, Y.K., Lin, C.H., Wang, P.W., Lin, J.Y., Fang, J.Y.* (2020) The absorption of polycyclic aromatic hydrocarbons into the skin to elicit cutaneous inflammation: the establishment of structure–permeation and in silico–in vitro–in vivo relationships. Chemosphere, 255, 126955.
- Yu, H.P., Liu, F.C., Lin, C.Y., Umoro, A., Trousil, J., Hwang, T.L., Fang, J.Y.* (2020) Suppression of neutrophilic inflammation can be modulated by the droplet size of anti-inflammatory nanoemulsions. Nanomedicine, 15, 773–791.
- Wu, C.Y.J., Chen, C.H., Lin, C.Y., Feng, L.Y., Lin, Y.C., Wei, K.C., Huang, C.Y., Fang, J.Y.*, Chen, P.Y. (2020) CCL5 of glioma-associated microglia/macrophages regulates glioma migration and invasion via calcium-dependent matrix metalloproteinase-2. Neuro-Oncology, 22, 253–266.
- Yu, H.P., Liu, F.C., Umoro, A., Lin, Z.C., Elzoghby, A.O., Hwang, T.L., Fang, J.Y.* (2020) Oleic acid-based nanosystems for mitigating acute respiratory distress syndrome in mice through neutrophil suppression: how the particulate size affects therapeutic efficiency. J. Nanobiotechnol., 18, 25.
- Lee, W.R., Lin, Y.K., Alalaiwe, A., Wang, P.W., Liu, P.Y., Fang, J.Y.* (2020) Fractional laser-mediated siRNA delivery for mitigating psoriasis-like lesions via IL-6 silencing. Mol. Ther.-Nucl. Acids, 19, 240–251.
- Chen, P.Y., Wu, C.Y.J., Fang, J.H., Chen, H.C., Feng, L.Y., Huang, C.Y., Wei, K.C., Fang, J.Y.*, Lin, C.Y. (2019) Functionl change of effector tumor-infiltrating CCR5+CD38+HLA-DR+CD8+ T cells in glioma microenvironment. Front. Immunol., 10, 2395.
- Weng, J.R., Huang, T.H., Lin, Z.C., Alalaiwe, A., Fang, J.Y.* (2019) Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation. Biomed. Pharmacother., 119, 109398.
- Hsiao, C.Y., Yang, S.C., Alalaiwe, A., Fang, J.Y.* (2019) Laser ablation and topical drug delivery: a review of recent advances. Expert Opin. Drug Deliv., 16, 937–952.
- Lin, C.Y., Hsu, C.Y., Elzoghby, A.O., Alalaiwe, A., Hwang, T.L., Fang, J.Y.* (2019) Oleic acid as the active agent and lipid matrix in cilomilast-loaded nanocarriers to assist PDE4 inhibition of activated neutrophils for mitigating psoriasis-like lesions. Acta Biomater., 90, 350–361.
- Fang, J.Y., Lin, C.H., Huang, T.H., Chuang, S.Y. (2019) In vivo rodent models of type 2 diabetes and their usefulness for evaluating flavonoid bioactivity. Nutrients, 11, 530.
- Lin, Z.C., Hsieh, P.W., Hwang, T.L., Chen, C.Y., Sung, C.T., Fang, J.Y.* (2018) Topical application of anthranilate derivatives ameliorates psoriatic inflammation in a mouse model by inhibiting keratinocyte-derived chemokine expression and neutrophil infiltration. FASEB J., 32, 6783–6795.
- Abdelmoneem, M.A., Mahmoud, M., Zaky, A., Helmy, M.W., Sallam, M., Fang, J.Y.*, Elkhodairy, K.A., Elzoghby, A.O. (2018) Dual-targeted casein micelles as green nanomedicine for synergistic phytotherapy of hepatocellular carcinoma. J. Control. Release, 287, 78–93.
- Elgohary, M.M., Helmy, M.W., Abdelfattah, E.Z.A., Ragab, D.M., Mortada, S.M., Fang, J.Y.*, Elzoghby, A.O. (2018) Targeting sialic acid residues on lung cancer cells by inhalable boronic acid-decorated albumin nanocomposites for combined chemo/herbal therapy. J. Control. Release, 285, 230–243.
- Chuang, S.Y., Lin, C.H., Sung, C.T., Fang, J.Y.* (2018) Murine models of psoriasis and their usefulness for drug discovery. Expert Opin. Drug Discov., 13, 551–562.
- Liu, F.C., Yu, H.P., Lin, C.Y., Elzoghby, A.O., Hwang, T.L., Fang, J.Y.* (2018) Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute lung injury: the effect of nanovesicular surface charge. J. Nanobiotechnol., 16, 35.
- Hsu, C.Y., Sung, C.T., Aljuffali, I.A., Chen, C.H., Hu, K.Y., Fang, J.Y.* (2018) Intravenous anti-MRSA phosphatiosomes mediate enhanced affinity to pulmonary surfactants for effective treatment of infectious pneumonia. Nanomed.-Nanotechnol. Biol. Med., 14, 215-225.
- Liu, K.S., Huang, T.H., Aljuffali, I.A., Chen, E.L., Wang, J.J., Fang, J.Y.* (2017) Exploring the structure-permeation relationship of topical tricyclic antidepressants used for skin analgesia. Int. J. Pharm., 523, 386–397.
- Hsieh, P.W., Hung, C.F., Lin, C.H., Huang, C.W., Fang, J.Y.* (2017) Anti-melasma codrug of retinoic acid assists cutaneous absorption with attenuated skin irritation. Eur. J. Pharm. Biopharm., 114, 154–163.
专利
- Fluorescent dye compositions and uses thereof, Chia-Yu Fang, Chih-Jen Wen, US9,855,346 B2, 美国, 2014/11/06-2034/11/06
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇来治疗异位性皮肤炎，王东弘、方嘉佑、杨世骏、黄泽宏，I670055，中华民国 2019/9/1-2038/4/10
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇来防止和/或抑制葡萄球菌属物种的生长以及生物膜形成，王东弘、方嘉佑、杨世骏、黄泽宏，I680756，中华民国 2020/1/1-2038/7/1
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇来预防和/或治疗乾癣，王东弘、方嘉佑、杨世骏、庄士亿、黄泽宏，I716940，中华民国 2021/1/21-2039/7/22
- 凝胶型防晒组成物，吴智元、杨世骏、王东弘、方嘉佑，I760745，中华民国 2022/4/11-2040/5/11
指导研究生论文
|
姓名 |
毕业年份 |
论 文 题 目 |
现职 |
|
张方馨 |
2024 |
Fractional laser and radiofrequency microneedling accelerate the skin delivery of nanoencapsulated drugs for treating hair follicle-related diseases |
研究助理 |
|
杨晓媛 |
2024 |
Topical propofol delivery for treating psoriasiform inflammation |
研究助理 |
|
李静 |
2023 |
The toxicity of furan compounds through skin absorption |
研究助理 |
|
张晏慈 |
2023 |
Dual anti-inflammatory and antimicrobial nanosystems for treating MRSA bacteremia via actively targeting to neutrophils |
美国德州安德森癌症中心進修博士班 |
|
G.R. Nirmal |
2022 |
Nanoparticles transduced near-infrared phototherapeutics for multimodal alleviation of psoriasiform lesions |
博后研究 (比利时 Ghent University) |
|
林承諭 |
2022 |
Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils for psoriasiform dermatitis alleviation |
博后研究 (美国 Duke University) |
|
魏榯誸 |
2022 |
The effect of Chinese medicine compounds on the mitigation of atopic dermatitis |
研究助理 |
|
林姿瑋 |
2022 |
The development of conjugated linoleic acid-loaded nanocarriers for attenuating adipogenesis |
研究助理 |
|
简旻瑜 |
2022 |
The combination of β-lactam antibiotics and platelet-rich plasma achieves synergistic bacterial eradication and skin regeneration in wound healing |
生技公司研发 |
|
李玫樺 |
2022 |
Multifunctional liposomes loaded with proteinase K and retinoic acid eradicate Cutibacterium acnes biofilm and reduce cutaneous proliferation for the aim of acne treatment |
生技公司研发 |
|
黄芷淇 |
2022 |
The effect of TiO2-containing mesoporous silica on the prevention of ultraviolet irradiation-induced skin aging and the adsorption of pollutants |
生技公司研发 |
|
黄昭容 |
2021 |
Cutaneous delivery of isoflavones for treating psoriasiform lesion |
研究助理 |
|
林芊郁 |
2021 |
Laser-assisted skin delivery of interleukin-6 siRNA-loaded nanocarriers for mitigating psoriasiform inflammation |
医材公司研发 |
|
罗珮琦 |
2021 |
Laser-assisted skin delivery of retinoic acid-loaded polylactic acid/poly(lactic-co-glycolic acid) nanocarriers for treating photoaging |
研究助理 |
|
Thi My Huyen Nguyen |
2021 |
The anthraquinone compounds from rhubarb extract for mitigating psoriasiform inflammation |
生医公司研发 |
|
陈韦彰 |
2021 |
The lipolysis activity of the compounds from rhubarb extract |
研究助理 |
|
李贤儒 |
2021 |
Bioactive effect of curcumin and its naturally occurring derivatives on 3T3-L1 adipocytes |
健康食品公司研发 |
|
林资展 |
2020 |
The investigation of novel anti-psoriatic agents: PDE4 inhibitors and active-targeting nanocarriers |
长庚科大研究员 |
|
吴智元 |
2020 |
Development of sunscreen-loaded mesoporous silica for protecting ultraviolet irradiation and air pollutant invasion |
药厂 R&D |
|
郑文婷 |
2020 |
Ablative lasers promote the skin delivery of platelet-rich plasma |
生技公司 R&D |
|
巫鈺茹 |
2020 |
Immune regulatory effect of tumor-infiltrating lymphocytes (TILs) and glioma-associated macrophages/microglia (GAMs) in glioma |
美国博后研究 |
|
连婉媜 |
2019 |
The establishment of structure-permeation relationship: flavanones and benzoxazinone derivative as the examples |
药厂R&D |
|
Ani Umoro |
2019 |
The effect of lipid nanocarriers with different particle sizes for suppressing human neutrophil activation: Acute lung injury as a disease model |
印尼药厂 |
|
杨雨青 |
2019 |
The drug-resistant pathogen inhibition by cationic nanoemulsions and furanoquinone derivatives |
研究助理 |
|
林婕瑀 |
2019 |
The relationship between percutaneous absorption and skin toxicity of polycyclic aromatic hydrocarbon compounds |
药厂 R&D |
|
陈君汉 |
2018 |
Absorptive and therapeutic impacts of silymarin-loaded nanocarriers on post-gastric bypass surgery and obesity animals |
嘉义长庚医师 |
|
刘珮莹 |
2018 |
Fractional lasers for promoting the cutaneous absorption of macromolecules: diseased skins as the diffusion barriers |
研究助理 |
|
陈雅萍 |
2018 |
Cationic nanostructured lipid carriers as the vehicles of oxacillin for improving the inhibitory activity against drug-resistant bacteria |
药厂 R&D |
|
陈恩立 |
2017 |
The establishment of structure-permeation relationship: tricyclic antidepressants and flavonoids as the examples |
研究助理 |
|
林承諭 |
2017 |
Development of cilomilast-loaded nanoformulations for inhibiting neutrophil activation: lipid nanoparticles and niosomes |
博后研究 |
|
黄昌尉 |
2016 |
Enhancement strategies of topical retinoic acid delivery: non-ablative fractional laser and co-drug |
药厂研發管理 |
|
翁依涵 |
2016 |
New formulations and compounds for anti-MRSA therapy: malleable liposomes and natural products |
仪器公司研发 |
|
戴攸珊 |
2016 |
Passive and active targeting of silibinin-loaded nanocarriers for treating hepatic fibrosis |
生技公司研发 |
|
廖伟君 |
2016 |
Methylation and esterification of magnolol for ameliorating cutaneous targeting and therapeutic index by topical application |
生技公司研发管理 |
|
胡凯茵 |
2015 |
Design and development of nanocarriers for drug targeting to pulmonary tissue |
研究助理 |
|
高筱晴 |
2015 |
The cutaneous delivery of drugs via diseased skins: psoriasis and atopic dermatitis as examples |
医美仪器产物专员 |
|
黄淳麟 |
2014 |
Development and investigation of multi-functional nanosystems for integrating bioimaging and drug delivery |
研究助理 |
|
张书豪 |
2014 |
Transdermal delivery systems of ketorolac ester prodrugs and hydroquinone-salicylic acid co-drugs |
财团法人药技中心 |
|
施惠琪 |
2014 |
Establishment of skin permeability profiles for drug and sunscreen absorption via photoaging skin |
生技公司研发 |
|
洪宜筠 |
2013 |
Evaluation of skin response treated by bioactive and toxic compounds using different experimental platforms: magnolol/honokiol and phthalates as the permeants |
药厂業務代表 |
|
黄雅慧 |
2013 |
Pharmacokinetics and bioimaging of nanostructured lipid carriers for anti-inflammation and angiography |
生技公司研发 |
|
沉逢鸣 |
2013 |
Preparation and evaluation of lipid nanoparticles for targeting to hair follicles |
药厂產品經理 |
|
张媛婷 |
2013 |
The effect of cationic nanosystems in human neutrophils |
药厂業務代表 |
|
李怡静 |
2012 |
Influence of resurfacing laser on skin delivery of drugs: the risk of excessive drug absorption and enhancement of skin permeability |
生技公司企划 |
|
陈浚责 |
2012 |
The co-drugs of conjugated hydroquinone/azelaic acid and hysroquinone/tranexamic acid for enhancing topical skin targeting and decreasing penetration through skin |
药厂專案管理 |
|
袁丞音 |
2012 |
Transdermal drug delivery enhanced by fractional erbium:YAG laser |
美国進修博士學位 |
|
杨诗韵 |
2011 |
Evaluation of drug and sunscreen permeation via skin irradiated with UVA and UVB: comparisons of normal skin and chronologically aged skin |
生技公司品管分析师 |
|
古明娟 |
2011 |
Development and evaluation of drug delivery systems for apomorphine and its prodrugs |
药厂研發 |
|
张惠雯 |
2010 |
Mechanistic studies of the skin delivery of lipid colloid systems with different oil/fatty ester ratios for both lipophilic and hydrophilic drugs |
药厂產品經理 |
|
张力文 |
2010 |
Topical/transdermal delivery of natural antioxidants |
药厂研發企劃 |
|
陈朝煌 |
2009 |
The physicochemical characteristics and pharmacokinetics of water-in-oil emulsions encapsulated with anti-bladder cancer drugs via intravesical route |
社区药局药师 |
|
蔡佳音 |
2009 |
Delivery of buprenorphine and its prodrugs formulated by lipid nanoparticles |
医院药师 |
|
纪政嫻 |
2009 |
The development and evaluation on drug delivery systems for anti-Parkinson’s drugs: nano-carriers for injection and transdermal delivery formulation |
分析检验公司讲师 |
|
陈志杰 |
2009 |
Permeability and proteomicprofiles of heavy metals delivered by skin route |
粧品公司负责人 |
|
卓柔孜 |
2008 |
Enhancement of transdermal drug delivery by erbium:YAG Laser: peptides, vaccine, and anti-psoriatic Drug |
生技公司研发 |
|
苏鈺涵 |
2008 |
The physicochemical characterization and drug delivery of lipid nanoparticles for topical and injectable dosage forms |
研究助理 |
|
黄梓柔 |
2008 |
Development and evaluation of resveratrol and soy Isoflavones in topical/transdermal delivery systems |
CRO 研究主管 |
|
叶智惠 |
2007 |
Design and characterization of drug delivery systems for narcotic prodrugs |
药厂研發 |
|
花淑秋 |
2007 |
Development and investigation of nano-or submicron-sized vesicles for encapsulating cisplatin and camptothecin |
医院药师 |
|
胡濬文 |
2007 |
The thermo-sensitive hydrogels containing chitosan, hyaluronic acid and alginate as drug delivery systems |
生技公司研发主管 |
|
廖美惠 |
2006 |
Drug delivery and in vivo efficacy of resveratrol from nano/submicron encapsulated formulations |
药厂業務代表 |
|
刘静儒 |
2006 |
Transdermal delivery of drugs and genes enhanced by microdermabrasion and Er:YAG laser |
药厂產品專員 |
|
黄妍菱 |
2005 |
The physicochemical characteristics and in vivo pharmacokinetics of tea catechins encapsulated with liposomes |
美国 |
|
翁玟雯 |
2005 |
Enhancing percutaneous absorption of theophylline and tea catechins by chemical and physical methods |
医院药师 |
|
王新元 |
2005 |
Hydrogels as drug carriers for both micro- and macromolecules |
药师 |
|
张嘉骏 |
2004 |
Nano/submicron lipid emulsions composed of natural oils modulate drug and gene delivery |
中医师 |
|
方逸萍 |
2004 |
Transdermal delivery of anti-cancer drugs promoted by physical enhancements |
高医大副教授 |
|
邱显智 |
2003 |
Evaluation of efficacy and safety on skin permeation enhancers: flurbiprofen and curcumin as model drugs |
马来西亚生技公司主管 |
|
郑晓菁 |
2003 |
Development of essential oils from Alpinia oxyphylla and Ocimum basilicum as novel skin permeation enhancers |
药厂研發 |