91猫先生

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生物医学研究所

生物医学研究所
:::
王蓮成

王蓮成 / Lian-Chen Wang

职称： 教授

现职： 长庚大学

信箱： wanglc@mail.cgu.edu.tw

电话： 5092

学歷： 高雄医学大学博士

专长领域：

个人网页：

研究方向及研究室特色：

A、广东住血线虫之研究
1. 广东住血线虫第叁期及第五期幼虫表现序列标帜之分析
2. 广东住血线虫分泌性蛋白的选殖与分析
3. 应用磁振造影於广东住血线虫症之探讨
4. 不同宿主感染广东住血线虫后脑部之病理学研究
5. 广东住血线虫免疫诊断方法之研究
B、寄生蟲疾病之流行病学調查

最近五年所发表论文：

  1. Chen, K.Y., Chen, Y.J., Cheng, C.J., Jhan, K.Y., . & . 2020. 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products. Biomedical Journal. 10.1016/j.bj.2020.11.008. (SCI)
  2. Cheng, C.C., Yang, C.F., Lo, Y.P., Chiang, Y.H., Sifiyatun, E., Wang, L.C. & Chen, W.J.2020. Cell-to-cell spread of dengue viral RNA in mosquito cells. BioMed Research International 10.1155/2020/2452409. (SCI)
  3. Jhan, K.Y., Lai, G.J., Chang, P.K., Tang, R.Y., Cheng, C.J., Chen, K.Y. & . 2020. Angiostrongylus cantonensis causes cognitive impairments in heavily infected BALB/c and C57BL/6 mice. Parasites & Vectors 10;13(1):405. (SCI)
  4. Chen, K.Y., Cheng, C.J., Cheng, C.C., Jhan K.Y., Chen, Y.J. & . 2020. The excretory/secretory products of fifthstage larval Angiostrongylus cantonensis induces autophagy via the Sonic hedgehog pathway in mouse brain astrocytes. PLOS Neglected Tropical Diseases 14(6): e0008290. (SCI)
  5. Chen, K.Y., Chen, Y.J., Cheng, C.J., Jhan, K.Y. & . 2020. Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes. Parasites & Vectors 18;13(1):317. (SCI)
  6. Chen, K.Y., Lu P.J., Cheng C.J., Jhan K.Y., Yeh J. S. & Wang, L.C. 2019. Proteomic analysis of excretory-secretory products from young adults of Angiostrongylus cantonensis. Memórias do Instituto Oswaldo Cruz 114:e180556. (SCI)
  7. International Helminth Genomes Consortium. 2019. Comparative genomics of the major parasitic worms. Nature Genetics 51(1): 163–174. (SCI)
  8. Wang, T. Y., Chen, K.Y., Jhan K.Y., Li, C. H., Jung, S. M. & Wang, L.C. 2018. Temporal-spatial expressions of interleukin-4, interleukin-10, and interleukin-13 in thebrains of C57BL/6 and BALB/c mice infected with Angiostrongylus cantonensis: An immunohistochemical study. Journal of microbiology, immunology, and infection .(SCI)
  9. Chen, T.H., Wu, Y.J.; Hou, J.N., Chiang, Y.H., Cheng, C.C., Sifiyatun, E., Chiu, C.H., Wang, L.C. & Chen, W.J. 2018. A novel p53 paralogue mediates antioxidant defense of mosquito cells to survive dengue virus replication. Virology 519: 516-519(SCI)
  10. ., ., . & . 2018. Enterobius vermicularis infection and its risk factors among pre-91猫先生 children in Taipei, Taiwan. Journal of microbiology, immunology, and infection 51(4):559-564(SCI)
  11. Lo, Y.L., Chen, C.L., Shen, L., Chen, Y.C., Wang, Y.H., Lee, C.C., Wang, L.C., Chuang, C.H., Janapatla, R.P., Chiu, C.H., Chang, H.Y. 2018. Characterization of the role of global regulator FliA in the pathophysiology of Pseudomonas aeruginosa infection. Research in Microbiology 169(3): 135-144(SCI)
  12. Chen, K.Y. & Wang, L.C. 2017. Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis. Parasites & vectors 10(1):445(SCI)
  13. ., . & . 2017. Anti-apoptotic effects of Sonic hedgehog signalling through oxidative stress reduction in astrocytes co-cultured with excretory-secretory products of larval Angiostrongylus cantonensis. Scientific Reports 7:41574(SCI)