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生物科技产业硕-博士学位学程

生物科技产业硕-博士学位学程
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張煥宗教授照片

張煥宗 / Huan-Tsung Chang

职称： 教授

现职： 生物醫學系 教授 / Professor

信箱： changht@mail.cgu.edu.tw

电话： 3020

学歷： 爱荷华州立大学博士

专长领域： 分析化学、奈米科学

个人网页：

研究主题

我们团队致力於绿色合成奈米材料，并将其应用於感测器、细胞影像、药物、奈米酵素、奈米催化剂及新能源等。研究重点如下：

(I)    金、银、铜及碳奈米点光学探针的开发

(II)   奈米药物的合成与其在抗菌、抗凝血和抗癌的应用

(III)  奈米微结构的组装和应用

(IV)  奈米材料於燃料电池、超级电容及二氧化碳还原的应用

发表着作

已在国际杂誌发表叁百九十九篇学术文章，代表着作為:

  1. Anand, A.; Jian, H.-J.; Huang, H.-H.; Hean, L.E.; Li, Y.-J.; Lai*, J.-Y.; Chou, H.-D.; Kang, E.Y.-C.; Wu, W.-C.; Lai, C.-C.; Huang, C.-C.; H.-T. Chang* “Anti-angiogenic Carbon Nanovesicles Loaded with Bevacizumab for the Treatment of Age-related Macular Degeneration” Carbon 2023, 2023, 201, 362-370.
  2. Lin, Y.-F.; Lin, Y.-S.; Huang, T.-Y.; Wei, S.-C.; Wu, R.-S.; Huang, C.-C.; Huang, Y-F.*; Chang, H.-T.* “Photoswitchable Carbon-dot Liposomes Mediate Catalytic Cascade Reactions for Amplified Dynamic Treatment of Tumor Cells” Journal of Colloid and Interface Sci. 2022, 628, 717–725.
  3. Wu, R.-S.; Lin, Y.-S.; Nain, A.; Unnikrishnan, B.; Lin, Y.-F.; Yang, C.-R.; Chen, T.-H.; Huang, Y.-F.*; Huang, C.-C.; Chang, H.-T.* “Evaluation of Chemotherapeutic Response in Living Cells Using Subcellular Organelle?Selective Amphipathic Carbon Dots” Biosens. Bioelectron. 2022, 211, 114362.
  4. Sangili, A.; Unnikrishnan, B.; Nain, A.; Hsu, Y.-J.; Wu, R.-S.; Huang, C.-C. *; Chang, H.-T.* “Stable Carbon Encapsulated Titanium Carbide MXene Aqueous lnk for Fabricating High-performance Supercapacitors” Energy Storage Mater. 2022, 53, 51?61.
  5. Lin, W.-J.; Lin, Y.-S.; Chang, H.-T.*; Unnikrishnan, B.; Huang, C.-C.* “Electrocatalytic CuBr@CuO Nanoparticles Based Salivary Glucose Probes” Biosens. Bioelectron. 2021, 194, 113610.
  6. Wu, C.-W.; Unnikrishnan, B.; Chen, I.-W. P.; Harroun, S. G.; Chang, H.-T.*; Hung, C.-C.* “Excellent Oxidation Resistive MXene Aqueous Ink for Micro-Supercapacitor Application” Energy Storage Mater. 2020, 25, 563?571.
  7. Xu, D.; Lin, Q.*; Chang, H.-T.* “Recent Advances and Sensing Applications of Carbon Dots” Small Methods 2019, 4, 1900387.
  8. Chen, T.-H.; Chang, H.-T.* “Stable and Photoswitchable Carbon-Dot Liposome” ACS Appl. Mater. Inter. 2017, 9, 44259–44263.
  9. Chen, P.-C.; Periasamy, A. P.; Harroun, S. G.; Wu, W.-P.; Chang, H.-T.* “Photoluminescence Sensing Systems Based on Copper, Gold and Silver Nanomaterials” Coord. Chem. Rev. 2016, 320, 129–138.
  10. Chen, W.-Y.; Chang, H.-Y.; Lu, J.-K.; Huang, Y.-C.; Harroun, S. G.; Tseng, Y.-T.; Li, Y.-J.; Huang, C.-C.; Chang, H.-T.* “Self-Assembly of Antimicrobial Peptides on Gold Nanodots: Against Multidrug-Resistant Bacteria and Wound Healing Application” Adv. Funct. Mater. 2015, 25, 7189–7199.
  11. Shih, C.-C.; Chen, P.-C.; Lin, G.-L.; Wang, C.-W.; Chang, H.-T.* “Optical and Electrochemical Applications of Silicon–Carbon Dots/Silicon Dioxide Nanocomposites” ACS Nano 2015, 9, 312–319.
  12. Hsu, P.-C.; Chang, H.-T.* “Synthesis of High-Quality Carbon Nanodots from Hydrophilic Compounds: Role of Functional Groups” Chem. Commun. 2012, 3984–3986
  13. Shiang, Y.-C.; Hsu, C.-L.; Huang, C.-C.*; Chang, H.-T.* “Gold Nanoparticles Presenting Hybridized Self-Assembled Aptamers That Exhibit Enhanced Inhibition of Thrombin” Angew. Chem. Int. Ed. 2011, 50, 7660–7665.
  14. Yang, Z.; Chen, C.-Y.; Liu, C.-W.; Li, C.-L.; Chang, H.-T.* “Quantum Dot-Sensitized Solar Cells Featuring CuS/CoS Electrodes Provide 4.1% Efficiency” Adv. Energy Mater. 2011, 1, 259–264.
  15. Chiang, C.-K.; Chen, W.-T.; Chang, H.-T.* “Nanoparticle-Based Mass Spectrometry for the Analysis of Biomolecules” Chem. Soc. Rev. 2011, 40, 1269–1281.
  16. Lan, G.-Y.; Huang, C.-C.; Chang, H.-T.* “Silver Nanoclusters as Fluorescent Probes for Selective and Sensitive Detection of Copper Ions” Chem. Commun. 2010, 46, 1257–1259.
  17. Yang, Z.; Chen, C.-Y.; Liu, C.-W.; Chang, H.-T.* “Electrocatalytic Sulfur Electrodes for CdS/CdSe Quantum Dot–Sensitized Solar Cells” Chem. Commun. 2010, 46, 5485–5487.
  18. Huang, C.-C.; Yang, Z.; Lee, K.-H.; Chang, H.-T.* “Synthesis of Highly Fluorescent Gold Nanoparticles for Sensing Mercury(II)” Angew. Chem. Int. Ed. 2007, 46, 6824-6828.
  19. Lin, Y.-W.; Tseng, W.-L.*; Chang, H.-T.* “Using a Layer-by-Layer Assembly Technique to Fabricate Multicolored-Light-Emitting Films of CdSe@CdS and CdTe Quantum Dots” Adv. Mater. 2006, 18, 1381-1386.
  20. Huang, C.-C.; Chang, H.-T.* “Selective Gold Nanoparticle-Based “Turn-On” Fluorescent Sensors for Detection of Mercury(II) in Aqueous Solution” Anal. Chem. 2006, 78, 8332–8338.

荣誉事项

获奖：

  1. Highly Cited Researchers, Clarivate Analytics 2017, 2018
  2. Prof. Rudolph A. Marcus Award 2017
  3. Academic Achievement Award, Chinese Chemical Society 2015
  4. Fellow of the Royal Society of Chemistry, UK 2013  
  5. Y. Z. Hsu Scientific Paper Award, Far Eastern Y. Z. Hsu Science and Technology Memorial Foundation 2008
  6. Outstanding Research Award, National Science Council 2007
  7. Fu Szu-Nien Award, National Taiwan University 2005
  8. Young Scientist Award, College of Science, National Taiwan University 2000
  9. Chinese Young Chemist Award, Chinese Chemical Society 2000

杂誌服务：

  1. Field Chief Editor: Frontiers in Analytical Science (2021~)
  2. Honorable Editor: International Journal of Biosensors & Bioelectronics (IJBSBE) (2016~)
  3. Executive Associate Editor: Analytical Sciences (2019~)
  4. Associate Editor: Journal of Chinese Chemical Society (2006-2014), Frontiers in Chemistry (Impact Factor: 5.545; 2013~; Analytical); Journal of Food and Drug Analysis (Impact Factor: 6.079; 2018~); Biosensors and Bioelectronics (Impact Factor: 12.545; 2019~)
  5. Editorial Advisory Board: Journal of Advanced Research (Impact factor: 12.822; Science; 2014~); JACS Au (2021~)