彭湛傑 / Jhan-Jie Peng, Ph.D.
职称： 助理研究员
现职： 长庚大学分子及臨床免疫中心助理研究员
电话： 2612
学歷： 长庚大学臨床醫學研究所博士
专长领域： 細胞治療 免疫治療
个人网页： https://pure.lib.cgu.edu.tw/zh/persons/jhan-jie-peng/
学歷
2025 长庚大学臨床醫學研究所博士2016 国立臺湾大学生化科学研究所硕士
2014 国立臺湾大学生命科学系学士
经歷
2025 长庚大学分子及臨床免疫中心 博士後研究員2021 - 2023 瑞士洛桑大學何秉智教授實驗室 訪問學者
荣誉
2025 Best thesis award, 沈水德翁文教基金會
2025 Best thesis award, The 21st Tien Te Lee Biomedical Awards
2021 Excellent performance in oral presentation, General Assembly and Academic Seminar, the Chinese Society of Immunology (CSI)
2019 FIMSA travel grant, The 17th International Congress of Immunology, International Union of Immunological Societies (IUIS)
2019 Excellent performance in oral presentation, General Assembly and Academic Seminar, CSI
2019 Best poster award, Formosa Immunology Spring School (FISS; One of thirty students
enrolled)
2018 Best poster award, Poster Competition in IBC, Academia Sinica
2016 Best poster award, Poster Competition in Institute of Biochemical Sciences, National Taiwan University
2015 Excellent performance in poster presentation, EMBO conference in Taiwan: neural development.
2015 Excellent poster and oral presentation performance, International Conference on Stem Cells and Developmental Biology Scientific Program.
2014 2nd place in the oral presentation competition, Taiwan Development Biology Retreat
2012 Excellent performance in the oral presentation, NPAS summer internship, Academia Sinica.
研究论文(选录)
Major publications- J. J. Peng, J. Y. Ding, Y. Xu, H. P. Shih, Y. N. Lin, T. Y. Wu, Y. F. Lo, C. C. Lo, C. F. Yeh, C. Y. Kuo, K. H. Tu, S. Y. Wang, W. T. Lei, T. S. Wu, H. S.Lin, C. H. Lee, W. C. Huang, Y. C. Chen, Y. M. Liu, Z. Y. Shi, Y. T. Chang, L. S. Syue, P. L. Chen, S. H. Teh, C. H. Chou, M. W. Ho, C. Y. Chi, P. C. Ho, C. L. Ku. Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ. First author. Sci Immunol 10, eadm8186 (2025)
- J. J. Peng, L Wang, Z Li, C. L. Ku, P. C. Ho. Metabolic challenges and interventions in CAR T-cell therapy. Co-first author. Sci Immunol 8, eabq3016 (2023).
- J.J. Peng, S.H. Lin, Y.T. Liu, H.C. Lin, T.N. Li, C.K. Yao Circuit-dependent ROS propagation mediates glutamate excitotoxicity to elicit motor system deficits in Drosophila. Co-first author. Elife 8, (2019).
- Y. Xu, Y. Shangguan, Y. M. Chuang, T. H. Chang, W. Liu, J. J. Peng, J. Garnica, L. Xie, P. C. Hsueh, M. C. Lin, Y. H. Wang, K. L. Hajdu, Y. Wu, M. Akrami, C. Wang, A. Kohl, A. Zippelius, W. Qi, M. Wang, B. R. Budiarto, S. Y. Chen, Z. Xiao, P. Vardaka, R. Roychoudhuri, Z. Bai, R. Fan, S. Carmona, Y. R. Yu, C. Scheiermann, J. Wang, P. C. Ho, Proteasome-guided haem signalling axis contributes to T cell exhaustion. Nature, (2026).
- X. Li, S. H. Moller, J. Park, Y. M. Chuang, P. C. Hsueh, T. H. Chang, K. C. Kao, H. Gallart-Ayala, Y. H. Wang, J. J. Peng, A. Bevilacqua, Y. R. Yu, Z. Li, Y. Kieffer, D. Peigney, H. Croizer, Y. Xu, A. Zippelius, I. C. Lopez-Mejia, L. Fajas, F. Mechta-Grigoriou, J. Ivanisevic, Z. Xiao, M. C. Ho, Y. C. Shen, P. C. Ho. Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes pro-tumor macrophages. J Exp Med 222 (2025).
- W. T. Lei, Y. F. Lo, M. Tsumura, J. Y. Ding, C. C. Lo, Y. N. Lin, C. W. Wang, L. H. Liu, H. P. Shih, J. J. Peng, T. Y. Wu, Y. P. Chan, C. X. Kang, S. Y. Wang, C. Y. Kuo, K. H. Tu, C. F. Yeh, Y. J. Hsieh, T. Asano, W. H. Chung, S. Okada, C. L. Ku. Immunophenotyping and Therapeutic Insights from Chronic Mucocutaneous Candidiasis Cases with STAT1 Gain-of-Function Mutations. J Clin Immunol 44, 184 (2024).
- Y. F. Lo, S. Y. Wang, Y. H. Wu, M. W. Ho, C. F. Yeh, T. Y. Wu, J. J. Peng, Y. N. Lin, J. Y. Ding, H. P. Shih, C. C. Lo, Y. P. Chan, C. S. Rau, C. Y. Kuo, K. H. Tu, W. T. Lei, Y. C. Chen, C. L. Ku. The Pathogenic Role of Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Nocardiosis with the Central Nervous System Involvement. J Clin Immunol 44, 176 (2024).
- A. Jaccard, T. Wyss, N. Maldonado-Perez, J. A. Rath, A. Bevilacqua, J. J. Peng, A. Lepez, C. Von Gunten, F. Franco, K. C. Kao, N. Camviel, F. Martin, B. Ghesquiere, D. Migliorini, C. Arber, P. Romero, P. C. Ho, M. Wenes. Reductive carboxylation epigenetically instructs T cell differentiation. Nature 621, 849-856 (2023).
- F. Franco, A. Bevilacqua, R. M. Wu, K. C. Kao, C. P. Lin, L. Rousseau, F. T. Peng, Y. M. Chuang, J. J. Peng, J. Park, Y. Xu, A. Cassotta, Y. R. Yu, D. E. Speiser, F. Sallusto, P. C. Ho. Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8(+) T cell formation. Sci Immunol 8, eadf7579 (2023).
- S. Y. Wang, Y. F. Lo, H. P. Shih, M. W. Ho, C. F. Yeh, J. J. Peng, H. T. Ting, K. H. Lin, W. C. Huang, Y. C. Chen, Y. H. Chiu, C. W. Hsu, Y. T. Tseng, L. S. Wang, W. Y. Lei, C. Y. Lin, Y. Aoh, C. H. Chou, T. Y. Wu, J. Y. Ding, C. C. Lo, Y. N. Lin, K. H. Tu, W. T. Lei, C. Y. Kuo, C. Y. Chi, C. L. Ku. Cryptococcus gattii Infection as the Major Clinical Manifestation in Patients with Autoantibodies Against Granulocyte-Macrophage Colony-Stimulating Factor. J Clin Immunol 42, 1730-1741 (2022).
- H. P. Shih, J. Y. Ding, J. Sotolongo Bellon, Y. F. Lo, P. H. Chung, H. T. Ting, J. J. Peng, T. Y. Wu, C. H. Lin, C. C. Lo, Y. N. Lin, C. F. Yeh, J. B. Chen, T. S. Wu, Y. M. Liu, C. Y. Kuo, S. Y. Wang, K. H. Tu, C. Y. Ng, W. T. Lei, Y. H. Tsai, J. H. Chen, Y. T. Chuang, J. Y. Huang, F. A. Rey, H. K. Chen, T. W. Chang, J. Piehler, C. Y. Chi, C. L. Ku. Pathogenic autoantibodies to IFN-gamma act through the impedance of receptor assembly and Fc-mediated response. J Exp Med 219, (2022).